Microtubule disassembly prevents palatal fusion and alters regulation of the E-cadherin/catenin complex
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چکیده
منابع مشابه
Microtubule disassembly prevents palatal fusion and alters regulation of the E-cadherin/catenin complex.
During palatal fusion, the midline epithelial seam (MES) degrades to achieve mesenchymal confluence. Epithelial mesenchymal transition (EMT) is one mechanism which is active in MES degradation. TGF-β induces EMT in medial edge epithelium (MEE) by down-regulation of an epithelial marker, E-cadherin. Microtubule disassembly impaired palatal fusion leading to a multi-layered MES in the mid-region....
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ژورنال
عنوان ژورنال: The International Journal of Developmental Biology
سال: 2013
ISSN: 0214-6282
DOI: 10.1387/ijdb.120117yk